What have you done regarding this issue? She knows it's a game so getting upset with her, telling her it's unacceptable, or calling her grandmother is feeding into the behavior. She is OLD ENOUGH to know better. What I would do, honestly, is put her in a play pen, tell her if she's going to act like a baby, she's going to be treated like a baby, and put her in a room by herself. Go check on her once in a while, and if she's being quiet or being good, praise her but don't let her out. At least for one day. For the next few days, make this area her time out area. EVERY TIME she starts screaming, pick her up and WORDLESSLY place her in the her area. DO NOT talk to her. Don't even explain to her why she's there, she knows why she's there. Continue to do this EVERY TIME and you will notice that eventually it will become less and less. If it doesn't improve within three weeks, I'd say, I would terminate. It sucks for the little girl because she obviously has her parents wrapped around her little finger, and other daycare providers keep giving up on her. If she starts kindergarten like that, she'll get kicked out. This is what I would so anyways. I am PRO TIME OUTS. They ALWAYS work. If they are not receiving ANY attention for their behaviour and they are being taken away from the other kids, they will start to realize it just doesn't work. Because, I'm assuming, right now, she receives more attention than the other kids - even if it is negative behaviour.