I wipe down surfaces (table in the playroom, kitchen playset, train table etc) every second day at least... I try to do it every day.

I only do a thourough washing of toys if there is something nasty going around. And even then, while I'm doing it i'm thinking, why am I doing this? everyone has been exposed! LOL

I wash the soft toys every week with the daycare bedding. I do the big toys every couple of months. I bleach when i'm trying to rid the house of something really contagious that I'm trying to get rid of.

I keep a bucket for toys that have gone into mouths and wash that stuff every day or two before I put it back in the toyroom.