I go overboard !!! Every night I wash all blankets I use (in the playpens) and wash the playpens down with a disinfecting wipe . All my tables and chairs and all my big toys are wiped down as well . I sweep and wash all the mats on the floor, the bathroom is done twice daily and the potty is wiped down each use . I throw the stuffies in the washer and dolls about twice a month .