I use my main floor living area as the playroom. One corner is the reading nook, it is enclosed with a couple of low bookcases, contains some soft kiddie chairs, pillows, basket with stuffed animals and a fish tank. In another corner is the kitchen area with a play stove/sink and a little mini table with shopping carts, mini stroller/ dolls / dress up bin. Near the kitchen area I have another bookcase that is the building area, it has all different types of blocks, legos, cubes etc...to build with. Then I have another shelf area with various toys.

I do all my crafts at our kitchen table as well as lunch and snack there. It's right next to our playroom.

To create these "centers" in your playroom, all I did was use my pieces of furniture to enclose my little reading area. I turned the kitchen sideways, instead of flat against the wall and it provides another little enclosed area. Kids like these little spots for them and it's easy to do with low bookcases etc...I'll take some pics and try to upload shortly.