I rotate my toys weekly all are washable, so around thursday and Friday all get washed. It helps not having too many. Friday all toys soaked and washed in dish soap or placed in the dishwasher. Shelves and the whole bathroom wiped with dawn soapy warm water. All daycare bedding in the washer machine as soon as they wake up from their nap on Fridays. So basically Monday all is sparkling clean. New toys and freshly laundered bedding and towels. I avoid using chemicals. Just Dawn dishsoap. It works.